Laboratory-acquired Brucellosis

Laboratory-acquired Brucellosis

We report two laboratory-acquired Brucella melitensis infections that were shown to be epidemiologically related. Blood culture isolates were initially misidentified because of variable Gram stain results, which led to misdiagnoses and subsequent laboratory exposures. Notifying laboratory personnel who unknowingly processed cultures from brucellosis patients is an important preventive measure.

Laboratory-acquired brucellosis.

Prevention of laboratory-acquired brucellosis: significant side effects of prophylaxis.

Reference 1. Lawn S, Wood R. How can earlier entry of patients into antiretroviral programs in low-income countries be promoted? Clin Infect Dis 2006; 42:431–2 (in this issue). Sir—We describe our experience in responding to a laboratory exposure to Bru-cella melitensis—in particular, the high incidence of adverse events associated with antibiotic prophylaxis. This information may be useful to ...

A Case-Study of Implementation of Improved Strategies for Prevention of Laboratory-acquired Brucellosis

BACKGROUND In 2012, the Alaska Section of Epidemiology investigated personnel potentially exposed to a Brucella suis isolate as it transited through three laboratories. METHODS We summarize the first implementation of the United States Centers for Disease Control and Prevention 2013 revised recommendations for monitoring such exposures: (1) risk classification; (2) antimicrobial postexposure ...

Update on laboratory diagnosis of human brucellosis.

The persistent worldwide prevalence of human brucellosis causes serious public health concerns and economic loss to communities. The multisystem involvement and the protean and unusual clinical presentations of the disease pose significant diagnostic challenges. The clinical features are non-specific and can overlap with a wide spectrum of other infectious and non-infectious diseases, leading t...